endocrine
17α-OH-Progesterone
17-OHP
Also known as 17-hydroxyprogesterone
Specification
- Method
- LC-MS/MS — steroid panel Liquid chromatography–tandem mass spectrometry
- Validated matrices
-
- Venous serum Standard draw
- Tasso capillary serum ~600 µL
- Tube
- RED
- CPT
83498- Reportable range
- 3.375 – 300 ng/dL
Clinical utility
Core marker in 21-hydroxylase deficiency. Immunoassay measurement has been shown to read 2–3.5× the structurally verified value.
Published reference ranges
Published values for 17α-OH-Progesterone vary along 4 axes:
- sex
- menstrual cycle phase
- time of day (AM)
- Tanner stage in adolescents
Stratified values are being transcribed from the cited source and are not yet published here. A single unstratified figure would be the least useful form of this information, so none is shown in the interim.
Published values vary by sex, age, time of collection, menstrual cycle phase and analytical method. The interval applicable to a patient's result appears on that patient's report.